Thiopental / Methohexital

IV Sedatives & Hypnotics

Smart Dose Calculator

Calculated Induction Dose
--mg

Mechanism of Action

Barbiturates binding GABA-A receptors. Potent cerebral vasoconstrictors that lower CBF, CMR, and ICP. Methohexital is commonly used for electroconvulsive therapy.

Dosage Guidelines

TypeRouteRate / Dose
Dosage/GuidelineSystemicThiopental Induction: 3–5 mg/kg IV; Methohexital: 1.5 mg/kg IV.