Physostigmine

Reversal Agents

Smart Dose Calculator

Calculated Induction Dose
--mg

Mechanism of Action

Tertiary amine cholinesterase inhibitor that crosses the BBB. Reverses central anticholinergic syndrome (e.g., scopolamine overdose) and treats postoperative shivering.

Dosage Guidelines

TypeRouteRate / Dose
Dosage/GuidelineSystemicDose: 0.01–0.03 mg/kg IV.