IV Sedatives & Hypnotics
Smart Dose Calculator
Calculated Induction Dose
--mg
Mechanism of Action
Water-soluble benzodiazepine. Provides anxiolysis and potent amnesia. Often used for preoperative medication or synergistic sedation.
Dosage Guidelines
| Type | Route | Rate / Dose |
|---|---|---|
| Dosage/Guideline | Systemic | Sedation: 0.05–0.1 mg/kg IV. |
Black Box Warnings
- Even small intravenous doses have resulted in respiratory arrest.
Clinical Pearls
1
Produces potent anterograde amnesia. Decreases MAC of volatile anesthetics by up to 30%. Reversed by flumazenil.