Methylene Blue

Reversal Agents / Antidotes

Smart Dose Calculator

Calculated Induction Dose
--mg

Mechanism of Action

Reduces methemoglobin (Fe3+) to hemoglobin (Fe2+).

Dosage Guidelines

TypeRouteRate / Dose
StandardIV1-2 mg/kg IV of 1% solution over 5 mins (max 7-8 mg/kg).

Clinical Pearls

1

Rapidly reverses life-threatening methemoglobinemia caused by local anesthetics like prilocaine or benzocaine.