Opioid Agonists
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Calculated Induction Dose
--mg
Mechanism of Action
Synthetic opioid with minor local anesthetic properties. Highly effective for postop shivering (kappa activity). Metabolite normeperidine causes neurotoxicity; interacting with MAOIs is potentially lethal.
Dosage Guidelines
| Type | Route | Rate / Dose |
|---|---|---|
| Dosage/Guideline | Systemic | Shivering: 10–25 mg IV. |