Local Anesthetics
Smart Dose Calculator
Calculated Induction Dose
--mg
Mechanism of Action
Amide local anesthetic; fast onset, medium duration. Serves as standard comparator. IV bolus (1.5 mg/kg) blunts airway reflexes and provides systemic analgesia.
Dosage Guidelines
| Type | Route | Rate / Dose |
|---|---|---|
| Dosage/Guideline | Systemic | Max dose: 4.5 mg/kg (plain) or 7 mg/kg (with epi). |
Black Box Warnings
- Local Anesthetic Systemic Toxicity (LAST): Progresses from circumoral numbness and tinnitus to seizures, coma, and respiratory/cardiac arrest.
Clinical Pearls
1
Fast onset and medium duration. Acts as a highly efficacious cardiac antidysrhythmic drug.