Local Anesthetics
Smart Dose Calculator
Calculated Induction Dose
--mg
Mechanism of Action
Blocks voltage-gated sodium channels; Pure S-enantiomer.
Dosage Guidelines
| Type | Route | Rate / Dose |
|---|---|---|
| Standard | Epidural/Spinal/PNB | 0.25-0.75%; Max dose: 150 mg. |
Black Box Warnings
- Systemic toxicity (LAST) leading to cardiovascular collapse and arrhythmias.
Clinical Pearls
1
Associated with less risk for cardiac and CNS toxicity compared to the racemic mixture bupivacaine.