IV Sedatives & Hypnotics
Smart Dose Calculator
Calculated Induction Dose
--mg
Mechanism of Action
Highly selective alpha-2 agonist. Provides cooperative sedation, anxiolysis, and analgesia without respiratory depression. May cause bradycardia and hypotension.
Dosage Guidelines
| Type | Route | Rate / Dose |
|---|---|---|
| Dosage/Guideline | Systemic | Load: 1 mcg/kg over 10 min; Infusion: 0.2–1.4 mcg/kg/h. |
Black Box Warnings
- Can cause severe bradycardia, hypotension, and even cardiac arrest. Long-term use can lead to acute withdrawal/hypertensive crisis upon abrupt discontinuation.
Clinical Pearls
1
Provides sedation, anxiolysis, and analgesia without significant respiratory depression. Patients are easily arousable.