Aprepitant

GI & Antiemetics

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Calculated Induction Dose
--mg

Mechanism of Action

Neurokinin-1 (NK1) receptor antagonist; inhibits substance P.

Dosage Guidelines

TypeRouteRate / Dose
StandardPO/IVOral / IV.

Clinical Pearls

1

Additive with ondansetron for PONV prophylaxis. Often reserved for patients at high risk of PONV due to cost.